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  1. Twenty One Zero-Days in FFmpeg (depthfirst.com)
    272 points by redbell 21 hours ago | 179 comments
  2. CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
    952 points by gmays 1 day ago | 205 comments
  3. There is a shadow hanging over this Fable thing (12gramsofcarbon.com)
    442 points by theahura 14 hours ago | 437 comments
  4. Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
    49 points by arcb 1 day ago | 23 comments
  5. Ask HN: Did we witness the "Trinity moment" for AI?
    9 points by vld_chk 1 hour ago | 7 comments
  6. What Happens to an Economy When It's Too Hot to Work? (bloomberg.com)
    8 points by littlexsparkee 56 minutes ago | discuss
  7. France's Own Hack Is the Best Argument Against Its War on Encryption (reclaimthenet.org)
    10 points by anonymousiam 2 hours ago | discuss
  8. Orthodox C++ (bkaradzic.github.io)
    63 points by signa11 6 hours ago | 77 comments
  9. Phone-Free Events Grew 567% Globally in 2026, over 900% in US Alone (eventbrite.com)
    5 points by karakoram 39 minutes ago | discuss
  10. Solar Overtakes Coal in US Electricity for the First Month on Record` (ember-energy.org)
    14 points by karakoram 3 hours ago | 4 comments
  11. Show HN: Lightweight Task queue on Erlang/OTP, SQLite-backed, no overengineering (github.com)
    66 points by ent1c3d 3 days ago | 10 comments
  12. If you are asking for human attention, demonstrate human effort (tombedor.dev)
    1655 points by jjfoooo4 2 days ago | 491 comments
  13. Tectonic: A modernized, complete, self-contained TeX/LaTeX engine (tectonic-typesetting.github.io)
    81 points by maxloh 4 days ago | 40 comments
  14. Stanford Scientists Regrow Lost Cartilage and Reverse Arthritis (sciencedaily.com)
    21 points by karakoram 4 hours ago | 2 comments
  15. How to setup a local coding agent on macOS (ikyle.me)
    467 points by kkm 1 day ago | 114 comments
  16. Sam Bankman-Fried loses bid to appeal against fraud conviction in FTX case (theguardian.com)
    77 points by pseudolus 7 hours ago | 64 comments
  17. Google proposes Open Knowledge Format based on Markdown (cloud.google.com)
    35 points by itherseed 5 hours ago | 5 comments
  18. A dumpster arrived behind my university's library (yalereview.org)
    171 points by mooreds 1 day ago | 168 comments
  19. What about OpenCL and CUDA C++ alternatives? (modular.com)
    19 points by eatonphil 4 days ago | 3 comments
  20. Do More with Less (biggestfish.substack.com)
    10 points by lilfrost 2 hours ago | discuss
  21. Show HN: Quant Picker – which GGUF file fits your model and machine (vettedconsumer.com)
    9 points by ermantrout 8 hours ago | discuss
  22. Automating Myself Out of Development (thoughtfultechnologist.com)
    73 points by nisabek 4 days ago | 40 comments
  23. AI forgoes toxic positivity for neurodivergents (medium.com)
    4 points by FDX2018 1 hour ago | discuss
  24. Malware developers added nuclear and biological weapons text to to their spyware (twitter.com)
    442 points by marc__1 2 days ago | 233 comments
  25. On CPU Physics and CPU Cycles (6it.dev)
    63 points by signa11 15 hours ago | 9 comments
  26. Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
    by augustschen 1 day ago
  27. Palantir loses legal challenge against Swiss investigative magazine (ft.com)
    388 points by sschueller 23 hours ago | 103 comments
  28. H.R. 6028 would fundamentally change the U.S. Copyright Office (eff.org)
    271 points by Cider9986 3 days ago | 120 comments
  29. The Future of wasi-gfx and wasi:webgpu (wasi-gfx.dev)
    37 points by mendyberger 4 days ago | 12 comments
  30. Swift at Apple: Migrating the TrueType hinting interpreter (swift.org)
    232 points by DASD 24 hours ago | 113 comments
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